Nomenclature

Gene Symbol
SNRPG (H. sapiens)
Other Gene Symbols
MGC117317, SMG, Sm-G
Full Name
small nuclear ribonucleoprotein polypeptide G
Other Names
SmG1, sm protein G, small nuclear ribonucleoprotein G, snRNP-G

Other Resources

Entrez: Gene Info
6637
Uniprot: Protein Info
RUXG_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
112521
PDB: Structures
2Y9A, 2Y9B, 2Y9C, 2Y9D, 3CW1
SpliProt3D: Structural Model
SNRPG

Gene Product Info

Molecular Weight (kD)
8.5
Domains
—
Motifs
—
Features
—
Complex Association
17S U2 snRNP, A complex, B complex, Bact complex, C complex, P complex, tri-snRNP, U1 snRNP, U4/U6 snRNP, U5 snRNP
Class / Family
Sm
Notes
—

Orthologs

Name Organism
SMX2 S. cerevisiae
smg1 S. pombe
SmG D. melanogaster
Y71F9B.4 C. elegans
FAM136A G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
SNRPG SNRPD3 Dervied from Literature — 9417867
SNRPG SNRPE Dervied from Literature — 9417867, 11226169
SNRPG SNRPF Dervied from Literature — 9417867
SNRPG SNRPF Y2H: Prey/Bait 1 22365833
SNRPG LSM3 Y2H: Bait/Prey 0.5 22365833
SNRPG SMN1 Dervied from Literature — 9323129, 10556282

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 374 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 287 21536652
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 284 21536652
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 281 21536652
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 212 21536652
U1 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 192 21536652
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 180 21386897
17S U2 snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 132 21536652
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 103 21386897
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 94 21386897
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 28 16809785
Saf1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 27 21386897
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 12 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 11 18322460
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 11 16809785
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 11 16809785
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 10 24448447
Bact complex, deltaPrp2 on M3Actin, Orbitrap, 0.25 pmol, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 9 19935684
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 9 27377154
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 8 18322460
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 8 20980672
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 8 20980672
Saf3 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 8 21386897
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 7 18322460
45SBact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 7 19935684
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 7 24448447
EDC-A complex Weri, H. sapiens, (Sharma et al 2008) H. sapiens 6 18193060
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 6 19935684
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 5 18193060
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 5 20980672
45S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 5 19935684
35S Bact complex, deltaPrp2 (+Prp2/Spp2) on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 5 19935684
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 5 24448447
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 4 19761775
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 4 18322460
Bact complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 4 19941820
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe 4 11884590
E-like complex (E') HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
EDC-A complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 4 18193060
Dre4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 4 21386897
40S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 75 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 4 19935684
Bact complex, deltaPrp2 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 4 23431055
Prp43 dissasociated ILS 5-6 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 4 23431055
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 4 27377154
B complex sample 1, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 3 19941820
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 3 18322460
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 3 18981222
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 3 17537823
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 3 17537823
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 3 18981222
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
28S B* complex, deltaPrp2 +Prp2/Spp2/ATP on M3Actin, 500 mM KCl wash, S. cerevisiae, (Warkocki et al 2009) S. cerevisiae 3 19935684
E complex IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 3 22110043
Prp43 dissasociated ILS 11-12 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
Prp43 dissasociated ILS 13-14 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 3 23431055
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 3 24448447
U2/U5/U6 complex CDC5-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 2 11884590
penta-snRNP, S. cerevisiae, (Stevens et al 2002) S. cerevisiae 2 11804584
B complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 2 19941820
EDC-E complex HeLa, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 2 12226669
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 2 18981222
Cwc21 tap-tag pulldown, S. cerevisiae, (Khanna et al 2009) S. cerevisiae 2 19789211
Post-catalytic complex, deltaPrp22 on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
ILS, released intron complex on M3Actin7, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
Prp43 dissasociated ILS 9-10 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 2 23431055
Bact complex sample 2, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
U2/U5/U6 complex Snt309-tag, S. cerevisiae, (Ohi et al 2002) S. cerevisiae 1 11884590
C complex on ActinD31, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
C complex on ActinACAC, S. cerevisiae, (Fabrizio et al 2009) S. cerevisiae 1 19941820
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 1 12226669
Prp43 dissasociated ILS 15-16 glycerol gradient fraction, S. cerevisiae, (Fourmann et al 2013) S. cerevisiae 1 23431055
tri-snRNP, S. cerevisiae, (Gottschalk et al 1999) S. cerevisiae ■ 10449419
U11/U12 18S di-snRNP, H. sapiens, (Will et al 2004) H. sapiens ■ 15146077
H complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
delta prp2 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
U2 17S, H. sapiens, (Will et al 2002) H. sapiens ■ 12234937
tri-snRNP, S. cerevisiae, (Stevens et al 1999) S. cerevisiae ■ 11720284
E complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
A-like complex (A') Weri, H. sapiens, (Sharma et al 2008) H. sapiens ■ 18193060
EDC complex, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
delta prp22 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
U1 snRNP, S. pombe, (Newo et al 2007) S. pombe ■ 17264129
H complex Weri, H. sapiens, (Sharma et al 2005) H. sapiens ■ 16109373
delta prp16 blocked spliceosome, S. cerevisiae, (Lardelli et al 2010) S. cerevisiae ■ 20089683
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
A complex, H. sapiens, (Hartmuth et al 2002) H. sapiens ■ 12477934
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945

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