Nomenclature

Gene Symbol
MFAP1 (H. sapiens)
Other Gene Symbols
—
Full Name
microfibrillar-associated protein 1

Other Resources

Entrez: Gene Info
4236
Uniprot: Protein Info
MFAP1_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
110394
PDB: Structures
—
SpliProt3D: Structural Model
MFAP1

Gene Product Info

Molecular Weight (kD)
52.0
Domains
—
Motifs
—
Features
—
Complex Association
B complex
Class / Family
Recruited at B complex
Notes
—

Orthologs

Name Organism
Mfap1 D. melanogaster
F43G9.10 C. elegans
MFAP1 G. gallus

View orthologs at Homologene

Interactions
(from Hegele et al, 2012)

Interacting Partner 1 Interacting Partner 2 Interaction Type Score PubMed ID
MFAP1 U2AF1 Y2H: Bait/Prey 0.5 22365833
MFAP1 PRPF3 Pull-down — 22365833
MFAP1 PRPF3 Y2H: Bidirectional 0.97 22365833
MFAP1 SART1 Y2H: Bait/Prey 0.5 22365833
MFAP1 SNW1 Y2H: Bait/Prey 0.5 22365833
MFAP1 SMU1 Y2H: Bidirectional 0.8 22365833
MFAP1 IK Pull-down — 22365833
MFAP1 IK Y2H: Bidirectional 1 22365833
MFAP1 DHX8 Y2H: Bait/Prey 0.75 22365833
MFAP1 DHX38 Y2H: Bait/Prey 0.5 22365833
MFAP1 SNIP1 Y2H: Bait/Prey 1 22365833
MFAP1 HSPB1 Y2H: Bait/Prey 0.5 22365833
MFAP1 FRA10AC1 Y2H: Bait/Prey 1 22365833

view interactions at SSPPIR...

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 94 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 62 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 49 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 45 24448447
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 41 20980672
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 37 18322460
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 36 20980672
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 25 21536652
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 25 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 23 16809785
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 23 16809785
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 19 20980672
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 19 16809785
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 18 16809785
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 18 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 15 27377154
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 13 20980672
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 12 21536652
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 10 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 10 24448447
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 7 18981222
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 7 21536652
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 7 27377154
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 6 18981222
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 6 23345524
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 5 18322460
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 5 18981222
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 5 27377154
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 4 18981222
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 4 24448447
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 3 12226669
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 3 23345524
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 2 18322460
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 2 11991638
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 2 18981222
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 1 18981222
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562

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