Nomenclature

Gene Symbol
SNRNP40 (H. sapiens)
Other Gene Symbols
40K, FLJ41108, HPRP8BP, MGC1910, PRP8BP
Full Name
small nuclear ribonucleoprotein 40kDa (U5)
Other Names
U5-40kD, 38 kDa-splicing factor, Prp8-binding protein, U5 small nuclear ribonucleoprotein 40 kDa protein, U5 snRNP 40 kDa protein, U5 snRNP-specific 40 kDa protein (hPrp8-binding)

Other Resources

Entrez: Gene Info
9410
Uniprot: Protein Info
SNR40_HUMAN
Organism-Specific Database
—
BioGrid: Interaction Info
114805
PDB: Structures
—
SpliProt3D: Structural Model
WDR57

Gene Product Info

Molecular Weight (kD)
39.3
Domains
—
Motifs
—
Features
—
Complex Association
B complex, Bact complex, C complex, P complex, tri-snRNP, U5 snRNP
Class / Family
U5 snRNP
Notes
—

Orthologs

Name Organism
spf38 S. pombe
CG3436 D. melanogaster
C18E3.5 C. elegans
F08G12.2 C. elegans
SNRNP40 G. gallus

View orthologs at Homologene

Identified in the following experiments:

Name Species # Of Peptides PubMed ID
Prp19 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 664 21386897
Cwf2 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 634 21386897
tri-snRNP, H. sapiens, (Agafonov et al 2011) H. sapiens 415 21536652
Prp17tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 367 21386897
C complex on PM5, H. sapiens, (Agafonov et al 2011) H. sapiens 333 21536652
Bact complex on PM5-20, H. sapiens, (Agafonov et al 2011) H. sapiens 328 21536652
B complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 321 21536652
B complex Sample#3, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 237 27377154
Pre-B complex Sample#3, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 141 27377154
A complex on MINX, H. sapiens, (Agafonov et al 2011) H. sapiens 88 21536652
B complex Sample#2, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 75 27377154
B complex Sample#1, on MINX-MS2 "kinetically" trapped, H. sapiens, (Boesler et al 2015) H. sapiens 70 27377154
Pre-B complex Sample#2, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 63 27377154
C complex on MINX-GG, H. sapiens, (Bessonov et al 2010) H. sapiens 60 20980672
Bact complex on PM5-10, H. sapiens, (Bessonov et al 2010) H. sapiens 48 20980672
C complex on PM5, H. sapiens, (Bessonov et al 2010) H. sapiens 47 20980672
Pre-B complex Sample#1, on MINX-MS2 stalled by DDX23 (hPrp28) depletion, H. sapiens, (Boesler et al 2015) H. sapiens 46 27377154
B complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 37 18322460
B complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 36 24448447
B complex via MS2 tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 34 16809785
Bact complex on PM5-20, H. sapiens, (Bessonov et al 2010) H. sapiens 32 20980672
C complex sample 2, H. sapiens, (Bessonov et al 2008) H. sapiens 29 18322460
C complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 29 18322460
C complex on PM5, sample 2, H. sapiens, (Schmidt et al 2014) H. sapiens 29 24448447
B complex via MS2 tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 28 16809785
Dre4 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 26 21386897
C complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 24 18981222
Saf3 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 24 21386897
B complex sample 1, H. sapiens, (Bessonov et al 2008) H. sapiens 23 18322460
B complex on Ftz, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 23 18981222
B complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 21 24448447
C complex, H. sapiens, (Ilagan et al 2009) H. sapiens 19 19761775
B complex via tobramycin tag, sample 2, H. sapiens, (Deckert et al 2006) H. sapiens 19 16809785
Saf1 tap-tag pulldown, S. pombe, (Ren et al 2011) S. pombe 18 21386897
P complex on AdML, short 3' exon, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 18 23345524
C complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 17 18981222
C complex on AdML, 3'SS mut, Velos, H. sapiens, (Ilagan et al 2013) H. sapiens 17 23345524
B complex on Ftz, sample 1, H. sapiens, (Herold et al 2009) H. sapiens 16 18981222
C complex 1M NaCl-washed core, H. sapiens, (Bessonov et al 2008) H. sapiens 15 18322460
C complex, H. sapiens, (Jurica et al 2002) H. sapiens 13 11991638
C complex released in 1M NaCl, H. sapiens, (Bessonov et al 2008) H. sapiens 12 18322460
B complex on Ftz, sample 2, H. sapiens, (Herold et al 2009) H. sapiens 10 18981222
Supraspliceosome, G. gallus, (Chen et al 2007) G. gallus 10 17537823
B complex on Zeste62, sample 3, D. melanogaster, (Herold et al 2009) D. melanogaster 10 18981222
B complex on Zeste62, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 9 18981222
C complex on PM5, sample 1, H. sapiens, (Schmidt et al 2014) H. sapiens 9 24448447
B complex on Ftz, sample 2, D. melanogaster, (Herold et al 2009) D. melanogaster 7 18981222
B complex via tobramycin tag, sample 1, H. sapiens, (Deckert et al 2006) H. sapiens 7 16809785
B complex on Zeste62, sample 1, D. melanogaster, (Herold et al 2009) D. melanogaster 6 18981222
C complex exons trimmed, H. sapiens, (Ilagan et al 2009) H. sapiens 5 19761775
Mixed spliceosome complexes on AdML, H. sapiens, (Zhou et al 2002) H. sapiens 5 12226669
Mixed spliceosome complexes on Ftz, H. sapiens, (Zhou et al 2002) H. sapiens 5 12226669
Supraspliceosome, H. sapiens, (Chen et al 2007) H. sapiens 5 17537823
Mixed complexes Weri, H. sapiens, (Sharma et al 2008) H. sapiens 3 18193060
C complex on AdML, maltose elute, H. sapiens, (Coltri et al 2011) H. sapiens 3 21526149
E-like complex (E') Weri, H. sapiens, (Sharma et al 2008) H. sapiens 2 18193060
mRNP on AdML, H. sapiens, (Merz et al 2007) H. sapiens 2 17095540
C complex on AdML, 3M urea wash, H. sapiens, (Coltri et al 2011) H. sapiens 2 21526149
H complex, H. sapiens, (Jurica et al 2002) H. sapiens 1 11991638
U2 snRNP IP'd by antibody to PRPF40A, H. sapiens, (Marakov et al 2011) H. sapiens 1 22110043
U5 35S complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
B* complex, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
tri-snRNP, H. sapiens, (Makarov et al 2002) H. sapiens ■ 12411573
Mixed spliceosome complexes, H. sapiens, (Neubauer et al 1999) H. sapiens ■ 9731529
Mixed spliceosome complexes, H. sapiens, (Rappsilber et al 2002) H. sapiens ■ 12176931
U2/U5/U6 complex CDC5-tag, S. pombe, (Ohi et al 2002) S. pombe ■ 11884590
Prp1 tap-tag pulldown, S. pombe, (Carnahan et al 2005) S. pombe ■ 15755920
PSF-pulldown, without splicing substrate, H. sapiens, (Peng et al 2006) H. sapiens ■ 17114945
B complex on MINX-MS2, ATPgammaS block, 40S glycerol gradient peak, H. sapiens, (Agafonov et al 2016) H. sapiens ■ 27411562

©2011 Spliceosome Component Database  All Rights Reserved.
design by juricalab